Scientists fed mice a special vitamin supplement called nicotinamide riboside in their food starting when the mice were middle-aged, then tracked how long they lived. The supplement didn't make the mice live longer.

13

Pro

0

Against

Evidence from Studies

Supporting (1)

13

Community contributions welcome

13

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Cohort Study

Animal

2021 May

The study tested nicotinamide riboside in the same type of mice (UM-HET3) mentioned in the claim and found it did not make the mice live longer. This matches what the claim says about no significant lifespan extension.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Score: 13

DOI: 10.1111/acel.13328

Similar Assertions

Scientists gave mice a supplement called nicotinamide riboside (NR) starting at 8 months old and found it didn't make them live longer or shorter compared to mice that didn't get the supplement.

13

0

94%

A popular anti-aging supplement called nicotinamide riboside (NR) was given to mice to see if it could help them live longer, but the study found it didn't extend their lifespan at the doses tested.

13

0

82%

Scientists fed old male mice a special chemical called 17-α-estradiol and found they lived about 19% longer than mice that didn't get the chemical.

13

0

71%