If you're on dialysis, taking 5 grams of creatine every day for a year might add about three-quarters of a liter of water inside your cells, which could help you gain lean body mass.

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Pro

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Against

Evidence from Studies

Supporting (1)

74

Community contributions welcome

74

Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

Randomized Controlled Trial

Human

2024 Feb 23

The study gave creatine to dialysis patients for a year and found their body water went up by 0.7 liters, mostly inside cells, which helps explain why their muscle mass appeared to increase.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

Score: 74

DOI: 10.3390/nu16050615

Similar Assertions

If you're on dialysis, taking a creatine supplement every day for a year might help your muscles hold more water and get bigger, and most people in the study saw some benefit.

74

0

96%

Taking a creatine supplement every day might help kidney patients on dialysis keep more muscle mass over time.

74

0

85%

Taking creatine for just a week can make young, healthy guys gain a little weight and look more muscular—even if they don’t work out, mostly because of water holding in their muscles.

60

0

82%

Taking creatine every day for two weeks doesn’t change how much water is in or around your cells — even though the balance between them might shift a little — at least in young women who work out regularly.

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78%

Taking creatine every day for a year doesn’t help improve nutrition or reduce inflammation in people on dialysis, according to this claim.

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77%