The Claim

In hemodialysis patients, daily supplementation with 5 grams of creatine monohydrate over 12 months leads to an average increase of 0.7 liters in total body water, primarily due to expansion of intracellular fluid, which may contribute to observed increases in fat-free mass as measured by bioimpedance analysis.

Source: Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
74score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

If you're on dialysis, taking 5 grams of creatine every day for a year might add about three-quarters of a liter of water inside your cells, which could help you gain lean body mass.

See the scientific wording

In hemodialysis patients, 5 grams of creatine monohydrate daily for 12 months increases total body water by 0.7 liters on average, primarily due to expansion of intracellular fluid, which may contribute to gains in fat-free mass as measured by bioimpedance analysis.

What the research says

1 study
  1. Study: Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

    The study gave creatine to dialysis patients for a year and found their body water went up by 0.7 liters, mostly inside cells, which helps explain why their muscle mass appeared to increase.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.