Consuming fructose from high-fructose corn syrup causes the liver to convert it into fat, which builds up in the liver as triglycerides.
Strongly supported
Multiple high-quality studies back this claim.
Not medical advice. For informational purposes only. Always consult a healthcare professional.
Consuming fructose from high-fructose corn syrup causes the liver to convert it into fat, which builds up in the liver as triglycerides.
See the technical phrasing
Dietary fructose, particularly from high-fructose corn syrup, is preferentially metabolized by the liver and promotes de novo lipogenesis, leading to hepatic triglyceride accumulation.
When fructose enters the liver, it is broken down in a way that floods the cell with building blocks for fat, turns on genes that make more fat, blocks the liver from burning fat, and forces the liver to pack that fat into triglycerides that get stored inside liver cells.
What the research says
Supports
3 studies
Study: Hepatic Adverse Effects of Fructose Consumption Independent of Overweight/Obesity
This study provides evidence supporting the claim.
Contradicts
0 studies
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 3 supporting studies