Consuming linoleic acid, a type of fat found in certain oils, leads to the production of molecules that bind to CB1 receptors in the brain, which can lead to an increase in hunger.

Sex-Specific Changes to Brain Fatty Acids, Plasmalogen, and Plasma Endocannabinoids in Offspring Exposed to Maternal and Postnatal High-Linoleic-Acid Diets

Enhanced 2-arachidonoyl glycerol-dependent CB1 activation contributes to feeding dysregulation in KK-Ay mice.