The Claim
Circulating levels of insulin-like growth factor 1 (IGF-1) and dehydroepiandrosterone sulfate (DHEA-S), as well as muscle mRNA expression of IGF-1, IGFR1, and myogenin, do not account for the observed gender difference in resistance-training-induced myofiber hypertrophy among older adults.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In older adults who do resistance training, the difference in muscle growth between men and women is not caused by differences in the blood levels of IGF-1 or DHEA-S, or by the activity levels of IGF-1, IGFR1, or myogenin genes in muscle tissue.
See the scientific wording
The observed gender difference in resistance-training-induced myofiber hypertrophy among older adults is not explained by circulating levels of insulin-like growth factor 1 (IGF-1) or dehydroepiandrosterone sulfate (DHEA-S), nor by muscle mRNA expression of IGF-1, IGFR1, or myogenin.
When older men and women lift weights, their muscles respond differently because their muscle fibers are activated in distinct patterns and their muscle repair cells respond differently, even though the same growth signals are present in both genders.
What the research says
1 studyStudy: Gender differences in resistance-training-induced myofiber hypertrophy among older adults.
Scientists found that when older men and women gain muscle from weight training, the difference between them isn’t because of the usual growth hormones or muscle genes they measured — so something else must be causing it.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.