mechanistic
Analysis v1
Strong Support
Dogs with an underactive thyroid might have higher levels of certain growth hormones, which could make their bodies less responsive to insulin.
8
0
Evidence from Studies
Supporting (1)
8
Community contributions welcome
8
Effect of hypothyroidism on insulin sensitivity and glucose tolerance in dogs.
Cross-Sectional Study
Animal
2012 AprThe study found that dogs with low thyroid function have higher levels of growth hormone and IGF-1, and also handle insulin worse, which supports the idea that these hormones might be part of the problem.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.