The Claim

In skeletal muscle tissue of young adult humans, eight weeks of high-intensity interval training leads to widespread DNA hypomethylation at 14,516 differentially methylated positions, indicating a broad epigenetic response to endurance exercise.

Source: Human skeletal muscle possesses an epigenetic memory of high intensity interval training affecting mitochondrial function

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
39score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

Doing intense interval workouts for 8 weeks can change how your genes are switched on or off in your muscles — and this study says it affects over 14,000 spots in your DNA.

See the scientific wording

In skeletal muscle of young adults, 8 weeks of high-intensity interval training induces widespread DNA hypomethylation at 14,516 differentially methylated positions, indicating a broad epigenetic response to endurance exercise.

What the research says

1 study
  1. Study: Human skeletal muscle possesses an epigenetic memory of high intensity interval training affecting mitochondrial function

    The study found that intense exercise training changed chemical tags on DNA in young adults' muscles, and the number of these changes matches exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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