Analysis Version
v1
History
Back to Study: Muscle damaging eccentric exercise attenuates disu...
correlational
Analysis v1
Strong Support

If young, healthy guys do certain tough leg exercises before keeping one leg still, they might avoid losing muscle in that leg during the first couple of days of not using it.

59
Pro
0
Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

59

Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men

Randomized Controlled Trial
Human
2021 Nov 1

The study found that doing tough muscle exercises before leg immobilization helps prevent early muscle loss in young men, just like the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men

Score: 59
DOI: 10.1152/ajpendo.00294.2021

Similar Assertions

If young, healthy guys do certain muscle exercises before having one leg kept still for a week, it doesn’t really help keep the muscle from shrinking — both those who did the exercises and those who didn’t lost about the same amount of muscle.

59
0
95%

If young, healthy guys do a tough leg workout right before having one leg immobilized for a week, their muscles in that leg keep building protein faster for the first couple of days compared to if they didn’t exercise first.

59
0
74%

If young, healthy guys do certain muscle-damaging exercises before their leg is immobilized, their muscles might waste away less—even if their muscle-building activity goes down. Without those exercises, lower muscle-building activity means more muscle loss.

59
0
72%

If young, healthy guys do certain muscle-lengthening exercises before having one leg kept still for a week, their muscles don’t slow down making new proteins as much as those who don’t exercise — which might help prevent muscle loss.

59
0
72%