For men who don't exercise much, doing regular leg press workouts with three sets at a moderate weight helps reduce overall body fat and thigh fat more than a different workout method, probably...

For guys who don't usually work out, doing regular weightlifting cuts more overall body fat and thigh fat than a special pre-exhaustion method over 9 weeks, probably because you lift more total weight with the regular way.

A shorter, easier leg workout gives the same muscle and strength gains as a longer, harder one for beginners, even though you're doing less overall work.

If young guys who don’t work out start doing 3 sets of leg exercises instead of 1, they’ll get stronger legs and bigger thigh muscles—41% stronger and 11% more muscle—but their arms and chest won’t see the same extra benefit from doing more sets.

A lighter warm-up exercise before heavier lifting gives the same muscle and strength gains as just doing the heavy lifting alone, even though you're doing less overall work.

Whether you use machines that change resistance as you lift or keep the same weight all the way through, after 20 weeks of training, healthy men gain about the same strength and muscle size either way.