Doing strength and cardio exercises at home for 13 weeks helps older adults (65–85) get stronger in their legs and move better, whether or not they're taking a drug called sirolimus.

In older adults who don't move much, taking a weekly rapamycin pill might slightly weaken the benefits of a 13-week home exercise program on leg strength and mobility, according to some detailed number crunching—even though the main results weren't clear-cut.

Older adults who take a weekly 6 mg dose of sirolimus while exercising might see slightly less improvement in hand strength and walking ability compared to those taking a fake pill — suggesting the drug could be limiting some of the usual benefits of exercise.

Taking a weekly low dose of a drug called rapamycin while doing a 13-week home exercise program might help older adults (65–85 years old) get stronger legs — but we’re not totally sure how much it helps because the study was small and short.

Taking a weekly 6 mg dose of the drug sirolimus doesn't help older adults get extra benefits from exercise — and might even cancel out some of the gains they'd normally see.

Light weight training helps older people move better by making it easier to stand up from a chair and walk faster after doing it twice a week for three months.