Drinking a glass of beetroot juice every day for a month can lower your blood pressure in different settings—like at home, at the doctor’s office, and even when you’re wearing a monitor all day—without your body getting used to it and losing the effect.

In adults diagnosed with hypertension, participants would receive 250 mL of beetroot juice (6.4 mmol nitrate) daily for 4 weeks versus an identical-looking placebo juice, with ambulatory, clinic, and home blood pressure measurements taken at baseline, mid-intervention (2 weeks), and end (4 weeks). Washout period of at least 2 weeks between phases. Primary outcome: mean change in systolic/diastolic BP across all three measurement types.

Two groups of adults with hypertension would be assigned to either daily 250 mL beetroot juice (6.4 mmol nitrate) or placebo for 4 weeks. Blood pressure would be measured at baseline and end using ambulatory, clinic, and home methods. Primary outcome: between-group difference in mean systolic/diastolic BP reduction. Secondary outcome: comparison of BP variability across measurement types.

All participants with hypertension would consume 250 mL beetroot juice daily for 4 weeks. Ambulatory, clinic, and home BP would be recorded at baseline and weekly for 4 weeks to assess trend and stability. Tolerance would be evaluated by comparing BP reduction at week 1 vs. week 4.

Adults with hypertension who voluntarily consume 250 mL beetroot juice daily for 4 weeks would be tracked via food diaries and BP logs. Changes in ambulatory, clinic, and home BP would be correlated with reported intake to assess real-world effect and adherence patterns.

A subset of participants from the RCT would undergo blood sampling at baseline, day 7, day 14, and day 28 to measure plasma nitrate/nitrite levels and endothelial function (e.g., flow-mediated dilation), to determine if BP reduction correlates with nitrate bioavailability and vascular response over time.