The Claim

Six weeks of daily dietary nitrate intake increases salivary nitrite concentration and alters the oral microbiome in hypercholesterolemic adults by increasing the relative abundance of Neisseria flavescens and trending to increase Rothia mucilaginosa.

Source: Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
74score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In adults with high cholesterol, consuming dietary nitrate daily for six weeks raises levels of nitrite in saliva and changes the types of bacteria in the mouth, specifically increasing Neisseria flavescens and slightly increasing Rothia mucilaginosa.

See the scientific wording

Six weeks of daily dietary nitrate intake increases salivary nitrite concentration and alters the oral microbiome in hypercholesterolemic adults, specifically increasing the relative abundance of Neisseria flavescens and trending to increase Rothia mucilaginosa, both nitrate-reducing bacteria.

Why this might work

When a person eats nitrate-rich food, the nitrate enters the saliva, where specific bacteria convert it into nitrite. These bacteria become more numerous after daily nitrate intake. The nitrite is swallowed and absorbed into the blood, where it is turned into nitric oxide. Nitric oxide relaxes blood vessels and reduces platelet stickiness, improving circulation.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study

    Drinking beetroot juice every day for six weeks changed the mouth bacteria in people with high cholesterol, increasing the good bacteria that turn nitrate into nitrite—exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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