The Claim

A single carbohydrate-rich meal suppresses fat mobilization for up to five days in individuals who have achieved nutritional ketosis, due to a prolonged inhibitory effect of insulin on lipolysis beyond its acute glucose-lowering action.

Source: Why hyperinsulinemia is detrimental to weight loss: insights from type 1 diabetes

What the research says

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How it works
1 study reviewed
In plain English

After achieving nutritional ketosis, consuming one carbohydrate-rich meal reduces the body's ability to break down fat for up to five days, because insulin continues to inhibit fat breakdown longer than it lowers blood glucose.

See the scientific wording

A single carbohydrate-rich meal can suppress fat mobilization for up to five days in individuals who have achieved nutritional ketosis, suggesting insulin has a prolonged inhibitory effect on lipolysis beyond its acute glucose-lowering action.

Why this might work

After eating a high-carb meal, insulin levels rise sharply and turn off fat-burning in fat cells. Even after insulin drops back down, the fat cells stay turned off for up to five days because the enzymes that break down fat remain inactive. This happens because insulin not only blocks those enzymes directly but also sticks around longer due to slow clearance, keeping the fat-burning switch off for days.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Why hyperinsulinemia is detrimental to weight loss: insights from type 1 diabetes

    Eating one high-carb meal while on a keto diet can stop your body from burning fat for up to five days, even after you go back to eating low-carb, because insulin keeps fat-burning turned off longer than you might expect.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.