The Claim

A high-protein diet is associated with a 3.48-fold increased relative risk of renal hyperfiltration, defined as estimated glomerular filtration rate >95th percentile after adjustment for confounders, in the general adult population.

Source: High-protein diet with renal hyperfiltration is associated with rapid decline rate of renal function: a community-based prospective cohort study.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
47score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Eating a lot of protein might make your kidneys work too hard, based on a big study of over 9,000 adults.

See the scientific wording

A high-protein diet is associated with a 3.48-fold increased relative risk of renal hyperfiltration (defined as estimated glomerular filtration rate >95th percentile after adjustment for confounders) in the general adult population, based on a community-based prospective cohort study of 9,226 subjects.

What the research says

1 study
  1. Study: High-protein diet with renal hyperfiltration is associated with rapid decline rate of renal function: a community-based prospective cohort study.

    The study looked at high-protein diets in a large group of adults and found that eating more protein raises the risk of kidney hyperfiltration by 3.48 times, which matches exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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