Eating more cholesterol from foods like eggs or liver is linked to higher bad cholesterol levels in people eating strictly controlled diets.

Scientific Claim

Higher dietary intake of dietary cholesterol is associated with higher levels of low-density lipoprotein cholesterol (LDL-C) in controlled feeding studies.

Original Statement

“Higher intakes of SFA, dietary cholesterol and TFA were each significantly associated with higher LDL-C levels”

From study:Abstract 18256: Importance of Controlling Dietary Intake of Saturated Fat for Prevention of Coronary Heart Disease: Lessons From the Metabolic Ward Studies

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study uses 'associated with' for dietary cholesterol, consistent with its controlled feeding design and lack of confirmed randomization. No causal language is used.

Evidence from Studies

Supporting (1)

Abstract 18256: Importance of Controlling Dietary Intake of Saturated Fat for Prevention of Coronary Heart Disease: Lessons From the Metabolic Ward Studies

Systematic Review With Meta-Analysis

Human

This study found that when people ate more cholesterol from food, their 'bad' cholesterol (LDL) went up — even when everything else they ate stayed the same.

Contradicting (0)

No contradicting evidence found

Source Study

Abstract 18256: Importance of Controlling Dietary Intake of Saturated Fat for Prevention of Coronary Heart Disease: Lessons From the Metabolic Ward Studies

Score: 54

DOI: 10.1161/circ.124.suppl_21.a18256

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