Claim
correlational

Eating more fiber—especially from whole grains—lowers your risk of heart disease and helps you live longer after a heart attack, probably by lowering bad cholesterol and stabilizing blood sugar.

Claim Context

Scientific statement

Dietary fiber intake, particularly cereal fiber, is associated with a 9% lower risk of coronary heart disease per 7g/day increase and a 27% lower risk of death after myocardial infarction, likely through reductions in LDL cholesterol and improved glucose control.

Original statement
In a meta-analysis of 22 cohorts, a 7g/d increase in fiber intake was associated with a 9% decrease in CHD incidence... Intake of fiber, particularly cereal fiber has also been shown to reduce all-cause mortality among MI survivors, with a 27% (HR 0.73, 95% CI: 0.58, 0.91) reduction in risk of...

Evidence from Studies

No evidence studies found yet.

What Would Prove This

Per GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this claim, ordered from strongest to weakest.

1
Systematic Reviews & Meta-Analyses
In Evidence

The pooled effect of fiber intake on CHD incidence and post-MI mortality across populations.

A systematic review and meta-analysis of 25+ prospective cohort studies (n>1.5 million) with validated fiber intake assessment, stratifying by fiber source (cereal, fruit, vegetable), adjusting for confounders, reporting HRs per 7g/day increase.

2
Randomized Controlled Trials
In Evidence

Whether increasing fiber intake reduces CHD events or post-MI mortality.

A double-blind RCT of 2,500 post-MI patients, randomized to 15g/day supplemental cereal fiber (e.g., oat bran) vs. placebo for 5 years, with primary outcome of all-cause mortality and secondary outcomes of LDL, HbA1c, and recurrent MI.

3
Cohort Studies
In Evidence

Long-term association between fiber intake and CHD incidence or post-MI survival.

A prospective cohort of 10,000 adults aged 40–75 followed for 20 years with repeated fiber intake assessments, measuring incident CHD and post-MI mortality.

4
Case-Control Studies
In Evidence

Whether individuals with CHD or post-MI death had lower prior fiber intake.

A case-control study of 1,200 CHD cases and 1,200 controls, using FFQs to assess fiber intake 5–10 years prior to event, matched for age, sex, and BMI.

5
Cross-Sectional Studies
In Evidence

Whether current fiber intake correlates with current lipid and glucose biomarkers.

A cross-sectional survey of 5,000 adults measuring fiber intake via 24-hour recalls and biomarkers (LDL, triglycerides, HbA1c) at a single time point.

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