Eating certain types of healthy fats—like those found in nuts and seeds—doesn’t seem to change levels of inflammation in the blood of healthy American adults.

If you're a healthy American adult eating a lot of certain vegetable oil fats (n-6), getting more fish oil fats (EPA and DHA) seems to help reduce signs of inflammation in your body. But if you're not eating much of those vegetable oil fats, the fish oil doesn't make much difference.

If healthy people in the U.S. regularly eat more foods rich in omega-3s like EPA and DHA—think fatty fish—their bodies tend to show lower levels of markers linked to chronic inflammation.

Eating more omega-3 fats — like those in fish and certain oils — is linked to fewer inflammation-causing cells in belly fat.

If older adults have more of a certain healthy fat (linoleic acid) in their blood cells, they tend to have lower levels of inflammation markers in their body.

Eating too much omega-6 fat—especially from vegetable oils and meat from grain-fed animals—might increase body-wide inflammation, which could lead to long-term health problems like heart disease or diabetes.