Eating sesame products doesn't change your fasting insulin levels. Researchers combined 8 smaller studies and found no significant effect.

Based on what we’ve reviewed so far, the evidence leans toward sesame products not having a meaningful effect on fasting insulin levels in adults. Our analysis of the available research found that a combined look at eight smaller studies supports this conclusion, with 39 supporting claims and none refuting it [1]. What this means is that when researchers pooled the data from those eight studies, they did not find a statistically significant change in fasting insulin after people ate sesame seeds or other sesame products. In other words, the current evidence we’ve examined suggests that adding sesame to your diet probably won’t raise or lower your fasting insulin in a noticeable way. That said, our analysis is based on the studies we’ve looked at so far, and future research could refine this picture. We are not saying this is definitive—only that the evidence we have now points in that direction. The practical takeaway: if you’re trying to manage your insulin levels, sesame seeds aren’t likely to be a game changer one way or the other. They can still be a nutritious addition to your diet for other reasons, but don’t rely on them to directly improve your fasting insulin numbers. As always, a balanced diet and overall lifestyle matter more than any single food.