Eating too much fructose over a long time can mess up how your liver responds to insulin, and that comes before your whole body becomes resistant to insulin—making your heart more at risk for disease.

From: John Yudkin’s hypothesis: sugar is a major dietary culprit in the development of cardiovascular disease

Strongly supported

Multiple high-quality studies back this claim.

1
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0
Against
correlational
1 study

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What this claim means

Eating too much fructose over a long time can mess up how your liver responds to insulin, and that comes before your whole body becomes resistant to insulin—making your heart more at risk for disease.

See the technical phrasing

Chronic excess fructose consumption is associated with the development of hepatic insulin resistance, which precedes whole-body insulin resistance and increases the risk of cardiovascular disease.

What the research says

Supports

1 study

1

Study: John Yudkin’s hypothesis: sugar is a major dietary culprit in the development of cardiovascular disease

This study provides evidence supporting the claim.

Contradicts

0 studies

0

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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