Eating too much fructose—like the sugar in soda and candy—can raise a substance in your blood called uric acid, which may damage your blood vessels, raise your blood pressure, and cause body-wide...

From: John Yudkin’s hypothesis: sugar is a major dietary culprit in the development of cardiovascular disease

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Multiple high-quality studies back this claim.

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mechanistic
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What this claim means

Eating too much fructose—like the sugar in soda and candy—can raise a substance in your blood called uric acid, which may damage your blood vessels, raise your blood pressure, and cause body-wide...

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Excess dietary fructose consumption is associated with elevated uric acid levels in humans, and this elevation in uric acid contributes to endothelial dysfunction, hypertension, and systemic inflammation, which are key risk factors for atherosclerosis.

What the research says

Supports

1 study

1

Study: John Yudkin’s hypothesis: sugar is a major dietary culprit in the development of cardiovascular disease

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