Even after eating a lot of fructose for a week, your body doesn’t burn fewer calories after meals — studies show your post-meal calorie burn stays the same.

Eating a lot of sugar with fructose for weeks doesn’t make your body burn fewer calories at rest — most studies show no change, and only one study saw a small drop under unusual conditions.

If you swap out sugary drinks and snacks for ones with artificial sweeteners, you might eat about 175 fewer calories a day, which could help you manage your weight.

If obese teens eat more fructose for a week — like swapping some carbs for sugary foods — but don’t eat more calories overall, it doesn’t seem to change how their body handles sugar or fat, at least in the short term.

If normal-weight women drink sugary drinks with fructose instead of glucose—making up 30% of their daily calories—it might cut their insulin response after meals by 65%, because fructose doesn’t trigger insulin like glucose does, which could affect how the body senses fullness or burns energy.

Using sugar-free sweeteners doesn’t make you eat more fat or protein than if you used regular sugar or just drank water—so their main job is just to cut down carbs and calories.