If young, healthy guys do certain muscle exercises before having one leg kept still for a week, it doesn’t really help keep the muscle from shrinking — both those who did the exercises and those who didn’t lost about the same amount of muscle.

59

Pro

0

Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

59

Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men

Randomized Controlled Trial

Human

2021 Nov 1

The study found that while eccentric exercise briefly protects muscles from wasting at first, after 7 days of not using the leg, both groups lost similar amounts of muscle, just like the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men

Score: 59

DOI: 10.1152/ajpendo.00294.2021

Similar Assertions

If young, healthy guys do certain tough leg exercises before keeping one leg still, they might avoid losing muscle in that leg during the first couple of days of not using it.

59

0

95%

If young, healthy guys do a tough leg workout right before having one leg immobilized for a week, their muscles in that leg keep building protein faster for the first couple of days compared to if they didn’t exercise first.

59

0

76%