The Claim
In overweight and obese adults with non-alcoholic fatty liver disease (NAFLD), a 6-day ketogenic diet is associated with a 58% improvement in hepatic insulin sensitivity, as measured by reductions in HOMA-IR and fasting insulin levels, despite an increase in circulating nonesterified fatty acids (NEFA), which challenges the conventional understanding that elevated NEFA levels contribute to insulin resistance.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Even though fat levels in the blood go up, a super low-carb diet for just 6 days seems to dramatically improve how well the liver responds to insulin in people with fatty liver and extra weight — which goes against what doctors usually expect.
See the scientific wording
In overweight and obese adults with NAFLD, a 6-day ketogenic diet is associated with a 58% improvement in hepatic insulin sensitivity, as indicated by reduced HOMA-IR and fasting insulin, despite increased circulating nonesterified fatty acids (NEFA), challenging the traditional view that elevated NEFA worsens insulin resistance.
What the research says
1 studyThe study found that a 6-day keto diet greatly improved liver insulin sensitivity in overweight people with fatty liver, even though fat levels in the blood went up — which usually makes things worse. This supports the claim.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.