The Claim
In uraemic erythrocytes, despite increased sodium-dependent creatine influx, intracellular creatine concentration does not exceed that in normal erythrocytes, suggesting that a factor present in uraemic plasma inhibits creatine accumulation under in vivo conditions.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Even though blood cells from people with kidney disease let in more creatine, they don’t end up with more creatine inside — probably because something in their blood is blocking it from building up.
See the scientific wording
Despite elevated sodium-dependent creatine influx, intracellular creatine concentration in uraemic erythrocytes is not higher than in normal erythrocytes, implying that a factor in uraemic plasma inhibits creatine accumulation during in vivo conditions.
What the research says
1 studyThe study found that even though uraemic red blood cells take in more creatine, their internal levels don't rise, suggesting something in the blood of uraemic patients blocks creatine buildup — just as the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.