The Claim
In male grey mouse lemurs, chronic 30% caloric restriction does not significantly alter performance in spatial memory (Barnes maze) or working memory (spontaneous alternation task) despite accelerated grey matter atrophy in memory-related brain regions.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In male grey mouse lemurs, a 30% reduction in calorie intake over time does not change performance on tests of spatial or working memory, even though brain regions involved in memory show increased tissue loss.
See the scientific wording
In male grey mouse lemurs, chronic 30% caloric restriction does not significantly alter performance in spatial memory (Barnes maze) or working memory (spontaneous alternation task) despite accelerated grey matter atrophy in memory-related brain regions.
Even though brain cells shrink and die in memory areas, the wiring between brain regions stays intact because the protective insulation around nerve fibers is preserved, allowing signals to travel normally and memory tasks to be performed without decline.
What the research says
1 studyStudy: Caloric restriction increases lifespan but affects brain integrity in grey mouse lemur primates
Even though the lemurs on a low-calorie diet lost more brain tissue in areas used for memory, they still remembered how to navigate mazes and make choices just as well as lemurs eating normally.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
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