The Claim

The four known lactase persistence-associated genetic variants (-13,910 C>T, -13,907 G, -13,915 G, and -14,010 C) do not account for the majority of lactase persistence phenotypes in populations across western Africa, the Balkans, and parts of South Asia.

Source: A worldwide correlation of lactase persistence phenotype and genotypes

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
51score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

In populations across western Africa, the Balkans, and parts of South Asia, most people can digest lactose as adults, but this trait is not primarily caused by the four known genetic variants linked to lactase persistence.

See the scientific wording

The four currently known lactase persistence-associated genetic variants (including -13,910 C>T, -13,907 G, -13,915 G, and -14,010 C) do not account for the majority of lactase persistence in populations across western Africa, the Balkans, and parts of South Asia, despite high phenotypic prevalence in these regions.

Why this might work

In some people, even without the known genetic changes, other changes in the DNA near the lactase gene keep the enzyme being made after infancy, allowing them to digest milk.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: A worldwide correlation of lactase persistence phenotype and genotypes

    Even though many people in parts of Africa and southern Europe can drink milk as adults, the known genes we thought caused this ability only explain some of the cases — so scientists know there must be other genes we haven’t found yet.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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