Even if your testosterone, growth hormone, and IGF-1 levels spike after a workout, that doesn’t mean you’ll grow more muscle over time—those hormone spikes don’t seem to explain why some guys get bigger than others after 16 weeks of lifting weights.
Claim Language
Language Strength
association
Uses association language (linked to, correlated with)
The claim uses 'are not associated with' and 'suggesting these... are not primary drivers,' which indicate a lack of correlation or influence rather than causation, placing it in the 'association' category.
Context Details
Domain
exercise_science
Population
human
Subject
young, untrained males
Action
are not associated with
Target
muscle hypertrophy after 16 weeks of resistance training
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Muscular and Systemic Correlates of Resistance Training-Induced Muscle Hypertrophy
The study found that even though young men had spikes in muscle-building hormones after workouts, those spikes didn’t predict who gained more muscle. Instead, what happened inside the muscle cells mattered more.