The Claim
Vitamin MK-7 supplementation at 375 μg/day for three years does not significantly alter bone turnover markers or bone microarchitecture in postmenopausal women with osteopenia, despite improving osteocalcin carboxylation.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking 375 micrograms of vitamin MK-7 daily for three years does not change bone turnover markers or bone structure in postmenopausal women with low bone density, even though it increases the activation of osteocalcin.
See the scientific wording
Vitamin MK-7 supplementation at 375 μg/day for three years does not significantly alter bone turnover markers or bone microarchitecture in postmenopausal women with osteopenia, despite improving osteocalcin carboxylation, indicating a disconnect between biochemical activity and structural bone outcomes.
Vitamin MK-7 activates a protein that helps bone minerals stick to the bone structure, but this does not change how quickly bone is broken down or rebuilt, so the overall strength and structure of the bone stay the same.
What the research says
1 studyEven though the vitamin made a key bone protein work better, it didn’t stop bones from getting weaker or change how fast they rebuild — so better protein activity didn’t mean better bones.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.