The Claim

In asymptomatic middle-aged U.S. adults with a coronary artery calcium (CAC) score of zero, the prevalence of any coronary plaque increases with higher LDL-cholesterol levels, ranging from 13.2% at LDL-C <70 mg/dL to 28.2% at LDL-C ≥190 mg/dL, with similar trends observed for noncalcified plaque.

Source: Low-density lipoprotein-cholesterol and subclinical coronary atherosclerosis in a middle-aged asymptomatic U.S. population: The Miami Heart Study at Baptist Health South Florida.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
29score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Even in healthy middle-aged Americans with no calcium in their heart arteries, higher 'bad' cholesterol levels are linked to more plaque buildup in the heart's blood vessels.

See the scientific wording

Among asymptomatic middle-aged U.S. adults with a coronary artery calcium (CAC) score of zero, the prevalence of any coronary plaque increases with LDL-cholesterol level, ranging from 13.2% at LDL-C <70 mg/dL to 28.2% at LDL-C ≥190 mg/dL, with similar trends observed for noncalcified plaque.

What the research says

1 study
  1. Study: Low-density lipoprotein-cholesterol and subclinical coronary atherosclerosis in a middle-aged asymptomatic U.S. population: The Miami Heart Study at Baptist Health South Florida.

    The study found that even when heart scans show no calcium, higher 'bad' cholesterol levels are linked to more hidden plaque in the heart's arteries, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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