The Claim
In fasted mice, lactate is the most abundant circulating metabolite on a molar basis, exhibits a turnover flux 60% higher than that of glucose, and functions as the primary carbon source feeding the TCA cycle in peripheral tissues under non-stressed conditions.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When mice haven't eaten, their blood has more lactate than any other fuel molecule—even more than sugar—and their body uses this lactate as the main fuel to power their cells, even when they're not stressed or in danger.
See the scientific wording
In fasted mice, lactate is the most abundant circulating metabolite on a molar basis, with a turnover flux 60% higher than glucose, and serves as the primary carbon source feeding the TCA cycle in peripheral tissues, even under non-stressed conditions.
What the research says
1 studyStudy: Impact of acute stress on murine metabolomics and metabolic flux
Even when mice haven’t eaten and aren’t stressed, their blood has more lactate than glucose, and their body uses that lactate as its main fuel for energy production — just like the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.