The Claim
In post-menopausal or ovariectomized women aged 46–65, acute hypercortisolism induced by pulsatile human corticotropin-releasing hormone does not suppress luteinizing hormone or follicle-stimulating hormone secretion, even at doses that significantly elevate cortisol.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In women who have gone through menopause or had their ovaries removed, a temporary surge in cortisol caused by a specific hormone injection does not reduce the levels of luteinizing hormone or follicle-stimulating hormone, even when cortisol levels rise significantly.
See the scientific wording
In post-menopausal or ovariectomized women aged 46–65, acute hypercortisolism induced by pulsatile human corticotropin-releasing hormone does not suppress luteinizing hormone or follicle-stimulating hormone secretion, even at doses that significantly elevate cortisol.
When cortisol rises sharply due to stress signals, it does not reduce the release of reproductive hormones in women who no longer have ovaries because the ovaries are gone and cannot send signals back to the brain to make it respond to cortisol.
What the research says
1 studyWhen scientists gave women who had gone through menopause a stress hormone trigger, their cortisol levels shot up—but their reproductive hormones stayed exactly the same. So, even under stress, these hormones didn’t drop.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.