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Back to Study: Myofibrillar protein synthesis rates are increased...
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Strong Support

In rats, lifting weights for two weeks made their muscles build more protein even though the usual muscle-building signals in their bodies went down. This shows muscles can grow without needing those normal signals.

7
Pro
0
Against

Evidence from Studies

Supporting (1)

7

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7

Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling

Cohort Study
Animal
2022 May 9

The study did the same exercise training in rats as described in the claim and found that muscle protein building went up even though the usual growth signals went down, which backs up the claim.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling

Score: 7
DOI: 10.1038/s41598-022-11621-x

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Your muscles make more protein at first when you start lifting weights, but after a few weeks, that boost fades—even if you keep lifting harder.

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Your muscles make more protein at first when you start lifting weights, but after a few weeks, that boost fades—even if you keep lifting harder.

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