For women who already train regularly, doing more resistance training each week does not lead to a measurable increase in the thickness of the outer thigh muscles after 12 weeks, even though other...
Mechanism
Synthesis from 1 study
In women who already train regularly, their thigh muscles have already grown as much as they can, so doing more workouts won’t make them thicker — even though they get stronger because their nerves become better at activating the muscles. This is shown in the study 10.1080/02640414.2025.2459003.
Most probable mechanism
In women who already train regularly, their thigh muscles have already grown as much as they can with their current training level, so doing more workouts doesn’t make them thicker — even though they get stronger from better nerve signaling. This is shown in the study that found more leg exercises didn’t increase outer thigh thickness after 12 weeks in trained females, despite strength gains.
Prior resistance training in females has already maximized muscle protein synthesis rates and myofibrillar packing density in the lateral thigh muscles, limiting further hypertrophic capacity despite increased volume.
Increased training volume enhances neural adaptations — such as motor unit recruitment and firing frequency — which improve strength without requiring additional muscle fiber growth.
Evidence from Studies
Supporting (1)
Community contributions welcome
Does increasing the resistance-training volume lead to greater gains? The effects of weekly set progressions on muscular adaptations in females
Contradicting (0)
Community contributions welcome
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.