Even if someone has very high 'bad' cholesterol, more than half of middle-aged people with no symptoms still show no signs of heart artery buildup — meaning their bodies might be naturally protecting...

If a middle-aged person has very high 'bad' cholesterol but feels fine, they’re more than 2.6 times as likely to have early signs of heart artery buildup — even if everything else about their health is accounted for.

If a middle-aged person has higher 'bad' cholesterol, they're more likely to have buildup in their heart arteries — every 38.7-point rise means about a 17% higher chance of early heart disease signs, even if they already have symptoms.

Even if a heart scan shows no calcium buildup, nearly 3 in 10 middle-aged people with high 'bad' cholesterol still have soft plaque in their arteries — meaning the usual heart risk test might miss early warning signs.

If you're a middle-aged person with signs of heart disease and calcium in your arteries, having very high 'bad' cholesterol makes your risk of heart problems more than double. But if your arteries are clean, even sky-high cholesterol doesn’t seem to increase your risk.

Even if someone has high 'bad' cholesterol, it doesn’t seem to reliably predict how much plaque is building up in their heart arteries — some people with very high levels have clean arteries, and their risk of heart events stays low if their scan shows no calcium.