When someone takes testosterone from outside their body, their brain stops telling their testicles to make their own testosterone, so they end up making none at all.
Evidence from Studies
Supporting (3)
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Testosterone deficiency and treatments: common misconceptions and practical guidance for patient care.
This study doesn’t test the mechanism directly, but it treats the idea that giving extra testosterone shuts down the body’s own production as common knowledge among doctors — meaning it supports the claim by not challenging it and assuming it’s true in clinical practice.
Taking extra testosterone makes your testicles stop making their own — this paper explains why that happens and how it causes infertility.
When men take extra testosterone, their brain stops telling their testes to make more testosterone — this paper shows that clearly in humans.
Contradicting (0)
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Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.