The Claim
The endocrine activity of epicardial fat, as characterized by its distinct protein secretion profile, is associated with the progression of cardiovascular disease.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Epicardial fat releases a different set of proteins than subcutaneous fat, and this difference is linked to the worsening of cardiovascular disease.
See the scientific wording
The endocrine activity of epicardial fat is associated with the progression of cardiovascular disease, as evidenced by its distinct protein secretion profile compared to subcutaneous fat.
Fat around the heart releases specific proteins that trigger inflammation in blood vessels, damage the vessel walls, and cause scarring, which leads to heart attacks and death. These proteins come out in much higher amounts from heart fat than from fat under the skin, and they directly enter the bloodstream to harm the heart and arteries.
What the research says
1 studyFat around the heart releases different and more harmful proteins than fat under the skin, and these proteins are linked to heart attacks and death. The study proves this difference exists and helps predict how bad heart disease will get.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.