If you're an adult with fatty liver disease, taking a supplement called GLS for 12 weeks along with healthy lifestyle changes might help you lose more belly fat and weight than another supplement, with an average of nearly 3.5 pounds more lost.

What we've found so far is that, for adults with fatty liver disease, taking a supplement called GLS along with lifestyle changes may lead to greater weight and belly fat loss compared to taking polyene phosphatidylcholine [1]. The evidence we've reviewed leans toward GLS being more effective for this purpose over a 12-week period. Our analysis of the available research shows that when adults with fatty liver disease follow healthy lifestyle changes and add GLS, they might lose nearly 3.5 pounds more than those using another supplement [1]. This finding is based on the data we’ve gathered so far, which includes 63.0 supporting assertions and no studies that refute this effect. While the evidence we’ve reviewed consistently supports this idea, we are still building our understanding and haven’t concluded anything definitively. We don’t yet know how GLS compares over longer periods or whether the results apply equally to all adults with fatty liver. Also, we haven’t reviewed evidence on side effects, cost, or long-term outcomes. Our current analysis only covers short-term weight and belly fat changes. It’s important to remember that this is what we’ve found up to this point—not a final answer. As more data becomes available, our understanding may change. Practical takeaway: If you’re an adult with fatty liver and are making lifestyle changes, adding GLS might help you lose a bit more weight and belly fat over 12 weeks than using polyene phosphatidylcholine, based on what we’ve seen so far.