The Claim

In adults with nonalcoholic fatty liver disease, a 12-week intervention with GLS at a dose of 8.12 g/day, combined with lifestyle modification, probably leads to greater improvements in body weight, waist circumference, and waist-to-hip ratio compared to polyene phosphatidylcholine, with a mean weight loss of 3.45 kg versus 1.95 kg, suggesting a beneficial effect on central adiposity and metabolic risk.

Source: An Open-Label Exploratory Clinical Trial Evaluating the Effects of GLS (Coptidis Rhizoma-Evodiae Fructus 2 : 1) on Fibroblast Growth Factor 21 in Patients with Nonalcoholic Fatty Liver Disease

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
63score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

If you're an adult with fatty liver disease, taking a supplement called GLS for 12 weeks along with healthy lifestyle changes might help you lose more belly fat and weight than another supplement, with an average of nearly 3.5 pounds more lost.

See the scientific wording

In adults with nonalcoholic fatty liver disease, 12 weeks of GLS (8.12 g/day) plus lifestyle intervention probably results in greater improvements in body weight, waist circumference, and waist-to-hip ratio compared to polyene phosphatidylcholine, with mean weight loss of 3.45 kg vs 1.95 kg, suggesting a beneficial effect on central adiposity and metabolic risk.

What the research says

1 study
  1. Study: An Open-Label Exploratory Clinical Trial Evaluating the Effects of GLS (Coptidis Rhizoma-Evodiae Fructus 2 : 1) on Fibroblast Growth Factor 21 in Patients with Nonalcoholic Fatty Liver Disease

    The study found that people who took GLS plus lifestyle advice lost more weight and belly fat than those who took a different supplement, which supports the idea that GLS helps improve health in people with fatty liver disease.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.