Fish oil can help protect your blood cells from damage at first, but if you take a lot for a long time, it ends up making them more fragile — and how much you take and how long you take it both matter.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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n-3 fatty acids induce oxidative modifications in human erythrocytes depending on dose and duration of dietary supplementation.

Cohort Study

Human

1996 Sep

At first, taking fish oil protects your red blood cells from damage, but after many months, especially with high doses, it makes them more vulnerable to damage instead.

Contradicting (0)

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No contradicting evidence found

Source Study

n-3 fatty acids induce oxidative modifications in human erythrocytes depending on dose and duration of dietary supplementation.

Score: 33

DOI: 10.1093/AJCN/64.3.297

Similar Assertions

People who take the highest dose of fish oil for six months end up with more oxidized fat in their red blood cells than those taking a low dose — even if they started with the same level of protection.

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