Taking fish oil supplements with EPA and DHA might help people with heart disease have healthier gums and lower their risk of heart problems, because it could reduce inflammation in the body and mouth.

We analyzed the available evidence on EPA and DHA supplements for people with coronary artery disease, and what we’ve found so far suggests these omega-3s may be linked to better gum health and lower heart risk, primarily through their potential to reduce inflammation in the body and mouth [1]. The evidence we’ve reviewed includes 57 assertions that support this idea, with none that contradict it. This doesn’t mean fish oil supplements fix gum disease or prevent heart events, but rather that the pattern in the data points toward a possible connection. Inflammation is a common thread in both gum disease and heart disease, and EPA and DHA are known to influence how the body responds to inflammation. What we’ve seen so far is that people taking these supplements often show signs of reduced inflammation markers, which could help both their gums and their arteries. We don’t know if the effect is strong, how long it takes, or if it works the same for everyone. The evidence doesn’t tell us whether taking fish oil is better than other ways to reduce inflammation, like diet or exercise. We also can’t say if the gum improvements directly lead to fewer heart problems, or if they’re just happening at the same time. Still, the consistent pattern across 57 assertions makes this worth considering, especially for people already managing heart disease. If you have coronary artery disease and are thinking about trying EPA and DHA supplements, talk to your doctor — they can help you decide if it fits your overall plan, and whether it’s safe with your other medications.