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Strong Support

For kidney transplant patients without diabetes, pravastatin can help protect the heart without raising the risk of getting diabetes.

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Pro
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Evidence from Studies

Supporting (1)

47

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47

#2667 The effect of pravastatin on insulin resistance in kidney transplant recipients. A randomized, placebo-controlled cross over trial

Randomized Controlled Trial
Human

This study gave kidney transplant patients pravastatin and checked if it made them more likely to get diabetes — it didn’t. Their blood sugar and insulin sensitivity stayed the same as when they took a placebo, so pravastatin is safe for their heart without hurting their sugar control.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

#2667 The effect of pravastatin on insulin resistance in kidney transplant recipients. A randomized, placebo-controlled cross over trial

Score: 47
DOI: 10.1093/ndt/gfaf116.1800

Similar Assertions

Taking pravastatin for 12 weeks didn't make the body better or worse at using insulin to control blood sugar in people who had a kidney transplant and don't have diabetes.

47
0
77%

Taking pravastatin for 3 months didn't raise or lower average blood sugar or long-term glucose control in kidney transplant patients without diabetes.

47
0
75%

Taking pravastatin for 3 months didn't harm the transplanted kidney's ability to work in patients without diabetes.

47
0
74%

After drinking a sugary solution, pravastatin didn't make blood sugar rise more or less than a placebo in kidney transplant patients without diabetes.

47
0
74%

Taking pravastatin for 12 weeks didn’t make the body better or worse at using insulin to control blood sugar in people with early-stage kidney disease who don’t have diabetes.

47
0
72%