Taking pravastatin for 12 weeks didn’t make the body better or worse at using insulin to control blood sugar in people with early-stage kidney disease who don’t have diabetes.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

#247 The effect of pravastatin on insulin resistance in patients with CKD stage 1-3. A randomized, placebo-controlled cross over trial

Randomized Controlled Trial

Human

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

#247 The effect of pravastatin on insulin resistance in patients with CKD stage 1-3. A randomized, placebo-controlled cross over trial

Score: 47

DOI: 10.1093/ndt/gfaf116.1325

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Taking pravastatin for 12 weeks didn't make the body better or worse at using insulin to control blood sugar in people who had a kidney transplant and don't have diabetes.

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After drinking a sugary solution, people with early kidney disease who took pravastatin had no meaningful difference in their blood sugar two hours later compared to those who took a sugar pill.

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