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Back to Study: #247 The effect of pravastatin on insulin resistan...
causal
Analysis v1
Strong Support

Taking pravastatin for 3 months didn’t raise or lower average blood sugar or long-term blood sugar control in people with early kidney disease who don’t have diabetes.

47
Pro
0
Against

Evidence from Studies

Supporting (1)

47

Community contributions welcome

47

#247 The effect of pravastatin on insulin resistance in patients with CKD stage 1-3. A randomized, placebo-controlled cross over trial

Randomized Controlled Trial
Human

This study gave 13 people with early kidney disease 40 mg of pravastatin daily for 12 weeks and checked their blood sugar and HbA1c before and after. It found no real change in either, meaning the drug didn’t raise or lower their blood sugar levels — just like the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

#247 The effect of pravastatin on insulin resistance in patients with CKD stage 1-3. A randomized, placebo-controlled cross over trial

Score: 47
DOI: 10.1093/ndt/gfaf116.1325

Similar Assertions

After drinking a sugary solution, people with early kidney disease who took pravastatin had no meaningful difference in their blood sugar two hours later compared to those who took a sugar pill.

47
0
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Taking pravastatin for 3 months didn't raise or lower average blood sugar or long-term glucose control in kidney transplant patients without diabetes.

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Taking pravastatin for 12 weeks didn’t make the body better or worse at using insulin to control blood sugar in people with early-stage kidney disease who don’t have diabetes.

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After drinking a sugary solution, pravastatin didn't make blood sugar rise more or less than a placebo in kidney transplant patients without diabetes.

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Taking pravastatin for 12 weeks didn't make the body better or worse at using insulin to control blood sugar in people who had a kidney transplant and don't have diabetes.

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