The Claim

In patients with a history of myocardial infarction, 2 weeks of time-restricted eating (8 a.m. to 2 p.m.) reduces neutrophil CD11b expression by approximately 22%, a marker of neutrophil activation linked to atherosclerotic plaque instability.

Source: Effect of 2 Weeks of Time‐Restricted Eating on Innate Immunity and Systemic Inflammation in Patients With a History of Myocardial Infarction: A Randomized‐Controlled Crossover Study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
84score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In people who have had a heart attack, eating only between 8 a.m. and 2 p.m. for two weeks lowers neutrophil CD11b expression by about 22%, a molecular marker associated with instability in atherosclerotic plaques.

See the scientific wording

In patients with a history of myocardial infarction, 2 weeks of time-restricted eating (8 a.m. to 2 p.m.) reduces neutrophil CD11b expression by approximately 22%, a marker of neutrophil activation linked to atherosclerotic plaque instability.

Why this might work

Eating only during a short window each day causes the body to burn fat for fuel, which increases ketone molecules in the blood. These ketones enter neutrophils and block a protein complex that triggers inflammation. This blockage stops the production of a key inflammatory signal, which in turn reduces the activation of neutrophils and lowers the expression of a surface molecule called CD11b that makes them stick to artery walls and cause damage.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Effect of 2 Weeks of Time‐Restricted Eating on Innate Immunity and Systemic Inflammation in Patients With a History of Myocardial Infarction: A Randomized‐Controlled Crossover Study

    For people who’ve had a heart attack, eating only between 8 a.m. and 2 p.m. for two weeks lowered a specific immune cell signal (CD11b) that’s linked to dangerous artery plaque — exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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