If someone with type 2 diabetes has stable 'bad' cholesterol but their triglycerides go up over a year, they’re more likely to develop dangerous plaque buildup in their heart arteries—even if everything else looks okay.

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Evidence from Studies

Supporting (1)

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Triglyceride levels predict high-risk coronary artery plaque progression in asymptomatic patients with type 2 diabetes and normal LDL cholesterol

Cohort Study

Human

The study shows that when triglyceride levels go up over a year in people with well-managed diabetes and cholesterol, their heart artery plaques get worse, just as the claim says.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Triglyceride levels predict high-risk coronary artery plaque progression in asymptomatic patients with type 2 diabetes and normal LDL cholesterol

Score: 37

DOI: 10.1093/eurheartj/ehad655.1387

Similar Assertions

Even if someone with type 2 diabetes has good cholesterol levels, high triglycerides might still mean their heart plaque is getting worse in dangerous ways.

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If you have type 2 diabetes but feel fine and your 'bad' cholesterol is under control, having higher triglycerides might still be quietly making your heart artery plaques more dangerous over time.

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For people with type 2 diabetes, the more harmful fat particles in their blood, the worse their heart disease tends to be.

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If you have type 2 diabetes but no symptoms and your 'bad' cholesterol is under control, what happens to your heart artery plaque over a year might depend on your triglycerides: going up could mean more plaque, while going down could mean less.

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Fat particles left over after digestion — called remnant lipoproteins — are thought to raise heart disease risk, especially when triglyceride levels are high.

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