The Claim
Among adults with type 2 diabetes, serum vitamin B12 levels below 369.1 pg/mL and above 703.5 pg/mL are both associated with a significantly higher risk of cardiovascular disease mortality compared to serum vitamin B12 levels between 369.1 and 506.0 pg/mL, indicating a U-shaped relationship in which both low and high levels of vitamin B12 may be harmful.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
For people with type 2 diabetes, having too little or too much vitamin B12 in the blood might increase the chance of dying from heart disease — the safest range seems to be in the middle.
See the scientific wording
Among adults with type 2 diabetes, serum vitamin B12 levels below 369.1 pg/mL and above 703.5 pg/mL are both associated with significantly higher risk of cardiovascular disease mortality compared to levels between 369.1–506.0 pg/mL, indicating a U-shaped relationship where both deficiency and excess may be harmful.
What the research says
1 studyThis study found that adults with type 2 diabetes who have either too little or too much vitamin B12 in their blood are more likely to die from heart disease, compared to those with levels in the middle range — just like the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.