The Claim

Among adults with type 2 diabetes, serum vitamin B12 levels above 703.5 pg/mL are associated with a 132% higher risk of cardiovascular disease mortality compared to serum vitamin B12 levels between 369.1–506.0 pg/mL, with this association representing the highest risk observed across all quartiles, suggesting that elevated B12 levels may serve as a marker of underlying pathology.

Source: Associations of Serum Folate and Vitamin B12 Levels With Cardiovascular Disease Mortality Among Patients With Type 2 Diabetes

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
59score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In people with type 2 diabetes, having very high levels of vitamin B12 in the blood seems to be linked to a much higher chance of dying from heart disease—higher than at any other B12 level—so maybe high B12 isn’t helping, but instead signals something else wrong in the body.

See the scientific wording

Among adults with type 2 diabetes, serum vitamin B12 levels above 703.5 pg/mL are associated with a 132% higher risk of cardiovascular disease mortality compared to levels between 369.1–506.0 pg/mL, the highest risk observed among all quartiles, suggesting that excessive B12 may be a marker of underlying pathology.

What the research says

1 study
  1. Study: Associations of Serum Folate and Vitamin B12 Levels With Cardiovascular Disease Mortality Among Patients With Type 2 Diabetes

    This study found that adults with type 2 diabetes who have very high levels of vitamin B12 in their blood are more likely to die from heart disease than those with moderate levels — exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.