Girls with early puberty who get a certain hormone treatment might grow about 2.5 cm taller on average than those who don’t get it, according to a review of several studies.

Girls with early puberty who get both a hormone blocker and growth hormone end up taller than expected—about 9 cm more—compared to those who only get the hormone blocker, which helps about 5 cm.

For girls who start puberty too early, a treatment using certain hormones can help them grow taller than expected — especially if they get a combo of two hormone treatments.

In girls who start puberty too early and are treated with a certain hormone therapy, those who are taller than average at the start, gain more weight in the first 6 months, or have higher levels of a growth-related hormone might grow faster during treatment — which could help doctors spot who will respond best early on.

For girls with early puberty who are treated with two hormones (one for puberty and one for growth), the ones who grow more during treatment tend to have started with a lower predicted adult height and more mature bones. How long or how much growth hormone they take doesn’t seem to affect how much they grow.

Giving certain hormone treatments to girls who start puberty too early can help them grow taller as adults.