Girls with early puberty who get both a hormone blocker and growth hormone end up taller than expected—about 9 cm more—compared to those who only get the hormone blocker, which helps about 5 cm.

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Pro

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Against

Evidence from Studies

Supporting (1)

50

Community contributions welcome

50

Effect of gonadotropin-releasing hormone agonist monotherapy and combination therapy with growth hormone on final adult height in girls with central precocious puberty

Cohort Study

Human

2023 Jan 23

The study found that girls who got both hormones grew taller than expected compared to those who got just one, which matches what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effect of gonadotropin-releasing hormone agonist monotherapy and combination therapy with growth hormone on final adult height in girls with central precocious puberty

Score: 50

DOI: 10.1038/s41598-023-28602-3

Similar Assertions

For girls with early puberty who are treated with two hormones (one for puberty and one for growth), the ones who grow more during treatment tend to have started with a lower predicted adult height and more mature bones. How long or how much growth hormone they take doesn’t seem to affect how much they grow.

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Girls with early puberty who get a certain hormone treatment might grow about 2.5 cm taller on average than those who don’t get it, according to a review of several studies.

66

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For girls who start puberty too early, a treatment using certain hormones can help them grow taller than expected — especially if they get a combo of two hormone treatments.

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91%

Girls with early puberty who get a combo of two treatments don't end up taller as adults than those who get just one treatment, even though the combo helps them grow more during treatment.

50

0

90%

Giving certain hormone treatments to girls who start puberty too early can help them grow taller as adults.

71

0

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