Girls with early puberty who get a combo of two treatments don't end up taller as adults than those who get just one treatment, even though the combo helps them grow more during treatment.

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Pro

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Against

Evidence from Studies

Supporting (1)

50

Community contributions welcome

50

Effect of gonadotropin-releasing hormone agonist monotherapy and combination therapy with growth hormone on final adult height in girls with central precocious puberty

Cohort Study

Human

2023 Jan 23

The study looked at two treatments for girls who start puberty early and found that both groups ended up about the same height as adults, even though the combo treatment helped girls grow more than expected.

Contradicting (0)

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No contradicting evidence found

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Source Study

Effect of gonadotropin-releasing hormone agonist monotherapy and combination therapy with growth hormone on final adult height in girls with central precocious puberty

Score: 50

DOI: 10.1038/s41598-023-28602-3

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Girls with early puberty who get a certain hormone treatment tend to grow about 3 inches taller as adults compared to those who don’t get it, according to a review of several studies.

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