When doctors raise a hormone called glucagon in healthy people's blood by giving them fatty acids, it doesn't change how much ketone (a chemical the liver makes) their bodies produce.

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Against

Evidence from Studies

Supporting (1)

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Fatty acid-independent inhibition of hepatic ketone body production by insulin in humans.

Cross-Sectional Study

Human

1988 Jun

The study tested whether raising glucagon levels while also raising fat levels in the blood affects how much ketone bodies the liver produces. They found that raising glucagon did NOT significantly change ketone body production, which matches what the claim says.

Contradicting (0)

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No contradicting evidence found

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Source Study

Fatty acid-independent inhibition of hepatic ketone body production by insulin in humans.

Score: 33

DOI: 10.1152/AJPENDO.1988.254.6.E694

Similar Assertions

When insulin levels get really high in the blood (around 110 units), it strongly stops the liver from making ketone bodies (which the body makes when breaking down fats), cutting the production rate by more than half in healthy people.

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When healthy adults haven't eaten overnight and have low insulin levels, having higher levels of fatty acids in their blood (about double the normal amount) makes their liver produce more than twice as many ketone bodies - the molecules your body makes when breaking down fat for energy.

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0

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When healthy adults have high levels of a hormone called glucagon in their blood, it causes a change in the balance of two specific ketone bodies (beta-hydroxybutyrate and acetoacetate) during a fat infusion procedure.

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73%